If you are looking for a fabulous 10-day Italy itinerary, you are in the right place!
Embarking on a 10-day journey through Italy was an absolute dream come true for us. As a Texas-based couple, passionate about travel, we immersed ourselves in the rich history, delectable cuisine, and breathtaking landscape of Rome, Florence, and Venice while on this Italian journey.
This itinerary is a culmination of our firsthand experiences, designed to help fellow travelers make the most of their Italian escape. We planned this route specifically for couples who want to see the major attractions but not feel overly rushed.
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10-Day Italy Itinerary at a Glance
- Day 1-4: Rome
- Day 5-7: Florence
- Day 8-10: Venice
Best time to visit: Spring (April-May) and Fall (September-October) for pleasant weather and fewer crowds.
Transportation: Efficient train systems connect major cities
Accommodation: Opt for centrally located hotels or B&Bs for an authentic Italian experience
Why This Itinerary Works (Based on Our Trip)



This Italy itinerary allows you enough time in each city to explore, without changing hotels too often. We try to base out of a few places and then have more time to dive deeper into each destination and take some day trips.
Granted, you won’t get to see everything, but we felt that this itinerary gave us a good taste of the major cities in the area and allowed us to explore day trips without moving around too much.
Days 1-4: Exploring Rome
Day 1: Trevi Fountain, Pantheon, Spanish Steps



Still a bit tired from jetlag, we decided to spend our first day exploring some iconic Roman attractions.
Granted, the Trevi Fountain is a must-see sight for any visitor to Rome, but be prepared for it to be crowded! We have visited the Trevi on three different trips to Rome, and every time it has been extremely crowded.
After snapping our pics of the Trevi, we mad our way to the incredible Pantheon, one of the best-preserved and most influential buildings in Rome.
The fascinating architecture and history of the structure kept us in awe during our visit. We couldn’t figure out why, but the Pantheon brings Marty to tears, LITERALLY. Even after returning home, all he has to do is think about the Pantheon, and he starts to cry.
I tease him that he must have built it in a former life?! I don’t know. Regardless, it is an incredible structure and the perfect introduction to the Eternal City.
End your first day in Rome by roaming the area around the Spanish Steps before finishing your evening enjoying the steps like the locals do.
Just remember…no sitting, eating, or loitering on the steps. This is banned and could result in a hefty fine.
Day 2: Colosseum, Roman Forum, and Palatine Hill
After getting some rest and a relatively relaxing day one, we hit the ground running on our second day in Rome to visit the most famous sights of Ancient Rome, the Colosseum, Roman Forum and Palatine Hill.
Visitors flock to Rome from all over the world to see the ancient sites left behind from when the Roman Empire ruled the world, and we were literally awestruck when we laid eyes on them.
The Colosseum

An iconic symbol of Rome, the Colosseum stands in the middle of the bustling city, serving homage to the past. Started by Emperor Vespasian around A.D. 70-72, the Colosseum was a gift to the Roman people and the site for various “games,” including gladiator fights.
While a general tour of the Colosseum is excellent, there is nothing like having access to the tunnels and seeing the stadium from the gladiator’s point of view! Trust us, we made it happen on our second trip.
Palatine Hill


Located above the Roman Forum with an entrance just outside the Colosseum, Palatine Hill is not to be missed. This was the home of Rome’s rich and famous and has been inhabited since 1000 B.C.
We chose to roam around independently, but if you want a more in-depth lesson on what you are looking at on Palatine Hill, you should consider a guided tour.
The Roman Forum

The final stop on our tour of Ancient Rome was the Roman Forum.
The Roman Forum was the hub of life in the Roman Empire. This is where all the crucial decisions were made regarding the ruling, politics, and even religion.
I loved walking around the “streets” Caesar walked on and seeing the remains of the temples, the arches, and the Senate House.
Like the other areas today, the Forum can be explored on your own, but if you want to know the history and hear the stories from this area, then take a guided tour and learn from the experts like we did!
Day 3: Vatican City- Vatican Museums, Sistine Chapel, and St. Peter’s Basilica

On day 3, we decided to visit the smallest country in the world, Vatican City, including, St. Peter’s Basilica, the Sistine Chapel, and the Vatican Museums.
Take Note- Be sure you are appropriately dressed for your visit; no bare knees or shoulders are allowed. also, they are closed on Sunday, except for the last Sunday of the month.
Home to the Pope and a pilgrimage site for millions of Christians, a trip to Vatican City is a must in Rome.
Marty and I did the after-hours tour and had a fabulous time. The crowds were smaller, and we got to skip the line thanks to our guided tour.
Day 3 Alternate Choice- Take a Day Trip or Food Tour
If you are not interested in visiting the Vatican during your Italy trip, you might consider taking a day trip or a fun food tour. Below are some suggestions that we have personally experienced and thoroughly enjoyed.
Day Trip to Tivoli

Tivoli is a short train ride outside of Rome and is home to the Villa d’Este, a gorgeous UNESCO World Heritage estate that boasts incredible gardens from the 1500s.
Day Trip to Capri


Ok, I am warning you now that if you choose to make this day trip, you must get up early as it will be a long day! The island of Capri, Italy, is one of my absolute favorite places on Earth, so I assure you it’s worth it.!
Get a ticket to Naples on the fast train from Rome’s Termini. Once in Naples, follow our guide on taking the Naples to Capri ferry and get on the FAST BOAT to Capri.
Visit the blue grotto, taste limoncello, and take the chair lift to the top of Mont Solaro for some of the most incredible views you have ever seen.
Food Tour in Rome



Taking a food tour in any city is a treat, but we especially loved our food tour in Rome.
We ate excellent food and tried unique Italian cocktails, while being introduced to new places and neighborhoods we might not normally have visited.
Day 4: Roman Catacombs and the Appian Way
For day four, we decided to take a little escape from the hustle and bustle of the crowded city center of Rome and head to the outskirts of town to explore the Ancient Appian Way and the Roman catacombs.
After taking a short, but crowded bus ride, we found ourselves on the Appian Way, a historic Roman road that has lasted thousands of years. There are many historic sites along the road, including the Roman Catacombs.

Day 5-7: Discovering Florence
Day 5: Travel to Florence, Visit the Duomo, and the Historic Center

On day 5, we said farewell to Rome and headed to Florence, one of the must-see towns in Tuscany.
Since frequent trains run from Rome to Florence, it was easy to grab our ticket at Rome’s central Termini station, validate it (important step) and be on our way!
Once we arrived in Florence, we took a local bus from the train station to our hotel, before heading out to explore the famous Duomo, the Cathedral di Santa Maria del Fiore.
This complex houses the nave, Brunelleschi’s Dome, Giotto’s Bell Tower, and the Baptistery, so we planned plenty of time to explore here.
We then spent the rest of the day relaxing and exploring Florence’s city center, visiting the Ponte Vecchio Bridge and Michelangelo’s Square.



Day 6: Day Trip to Tuscany or Cinque Terre
For day 6 of our itinerary, you have the option of taking a day trip to the beautiful Tuscan countryside to tour some small towns and do some wine tasting, or head to the coast to experience Italy’s beautiful towns of Cinque Terre with a day trip to Cinque Terre and some hiking in Cinque Terre.
Choosing just one is a hard thing to do. We have personally done toured both of these areas and loved them!
Tuscany is sprawling with gorgeous vineyards, rustic charm, and medieval towns, while Cinque Terre comprises five pretty hillside villages that are just picturesque.






If you’re opting for the 5 hillside coastal towns of Cinque Terre trip, this Cinque Terre in a day is a great way to go!
Either choice is great and you really can’t go wrong here.
Day 7: Uffizi Gallery, San Lorenzo Market



On day 7 of our itinerary, we started our morning with a visit to the Uffizi Gallery, one of the most famous museums in the world.
This former home of the Medici family is now a sprawling art museum with famous works from Leonardo di Vinci, Michelangelo, and Raphael, to name a few.
After the gallery, we toured the gorgeous Pitti Palace, the once opulent Medici family home, and the Boboli Gardens, both of which were stunning.
After all that time inside, I was ready for some fresh air, wo we grabbed a delicious Italian gelato and headed to the San Lorenzo Market, a great outdoor market perfect for finding leather, souvenirs, and pottery.
Days 8-10: Venice
Day 8: Arrive in Venice, Grand Canal Tour, Doge’s Palace, St. Mark’s Square and Basilica, Bridge of Sighs

On day 8, we took a train from Florence to Venice, one of my favorite Italian cities.
We chose to stay in a little bed and breakfast that was off the beaten path in an area’s where locals lived, and we loved it. I give you the detail in our 3 days in Venice post.
We had a lot of sights to see today, but luckily they were all located in the same area. Fair warning though, the area we are visiting today gets VERY CROWDED, so gather your patience.
Grand Canal Tour
We began our time in Venice by taking a tour of the Grand Canal (well, a self-made tour.) We learned this can be done quickly and cheaply by hopping the #1 or #2 Vaporetto, so that is exactly what we did.
Note that this is a water taxi, so it will stop at several stops along the way. If you prefer, you can also book a private Grand Canal tour.
St Mark’s Square, Basilica, and Doge’s Palace
We concluded our Grand Canal tour in St. Mark’s Square, the location for all of the iconic sights on today’s itinerary: the Bridge of Sighs, Doge’s Palace, the square, and St. Mark’s Basilica.

Doge’s Palace was commissioned in 1340 and extensively modified throughout the years, the Palace was home to numerous Doges who ruled over Venice throughout history.
If I were you, I would book the Doge’s Palace Secret Itineraries Tour before arriving in Venice.
This popular tour takes you through the palace, including several ‘off-limits’ places and we LOVED it! This was truly one of my favorite tours we have ever done.

After touring the palace, we headed to St. Mark’s Square and Basilica to face the crowds.
Take all the action around the square, tour the church, and climb the clock tower while in this area.
Dubbed the ‘church of gold’ due to all the gold you see adorning the church, St. Mark’s is a sight to behold! For an extra special treat, while not do an after-hours tour of the Basilica.
Day 9: Day Trip to Murano and Burano
Day 9 of our trip took us to the Venetian Islands of Murano, and Burano.
Murano, known for its famous hand-blown glass, and Burano, famous for its handmade lace and gorgeous colorful houses, were delightful to visit and truly a highlight of our time in Venice.
While we used the Vaporetto to get to the islands, let me warn you that it was a slow trip! If we were to go again, I would book a private tour by motorboat to the islands.


Day 10: Rialto Bridge and Market, Food Tour, Wander the City’s Charming Alleys
Rialto Bridge and Market

We got up early on day 10 so we could visit the bustling Rialto Market.
I absolutely adored seeing the locals interact with the vendors and they purchased their fresh fish, vegetables, and flowers. Seeing Venice through the local’s eyes was delightful and definitely an enjoyable experience.
The market is open Tuesday through Saturday from around 8:00 a.m. to noon.
After the market, we explored the shops on and near the Rialto Bridge as we waited for our food tour!
Venice Food Tour

One of our favorite things to do in any city is to take a food tour.
We loved this Cicchetti and wine tour.
Tasting so many local specialties was fun while being led by a knowledgeable local guide. I highly recommend it to be part of your itinerary.
If that tour isn’t for you, don’t worry; there are several Venice food tours.
Wander the Charming Alleys

For our final evening in Venice, we spent some time just getting lost.
Venice is such a magical place and is even more beautiful at night. Roam around, ducking into hidden alleys and passageways.
This was one of our favorite things to do in Venice as we constantly found hidden gems waiting to be photographed.
What We’d Do Differently Next Time
- Research and book popular tours and activities far in advance to ensure we were able to see and do everything we wanted on the days we were there
- Ensure we had appropriate clothing to visit the museums (no bar knees or shoulders)
- Travel during shoulder season instead of the summer to avoid some of the crowds and the heat
- Book the Vatican tour for either after hours or first thing in the morning as it gets VERY CROWDED during the day and it’s hard to see everything
- Make time to build in some “down time” to linger longer in a museum, or slow down and enjoy a long meal
- Book the underground tour at the Colosseum well in advance, and tour the Colosseum right when it opens or later in the evening to avoid the crowds and the direct heat from the sun
- Look for “osterias” or “trattorias” and ask the locals where they eat when dining out. The times we did this, the meals were outstanding when compared to restaurants near major squares or tourist areas
- Wake up early while in Rome to see the Trevi Fountain without all of the crowds
- Book our train tickets at least a month in advance using Omio or Trenitalia
10-Day Italy Itinerary – Final Thoughts
We hope you will take the suggestions in our 10-day Italy Itinerary and that we have helped you plan your trip to Italy.
If you have more time, include a few other day trips from your destination, or slow down and enjoy more of the city.
We fell in love with Italy on our first visit and have been back several times since. I hope our resources help you fall in love with Italy also!
Happy Travels, Friends!
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Michelle Snell– Founder/Writer
Michelle is a Texas-based travel creator who has spent years exploring Texas, Europe, Mexico, and destinations across the U.S. She shares thoughtful, experience-based travel guides focused on great scenery, good food, and easy, enjoyable trips.
Born and raised in Texas, Michelle Snell graduated with a Bachelor’s Degree from the University of Texas at Arlington and her Master’s Degree from Texas Wesleyan University. Her passion for travel has taken her all over the world. She has received multiple awards for her writing. She has been featured in numerous publications, including Travel Awaits, Fort Worth Magazine, Fort Worth Weekly, NewsBreak, Voyage Dallas, Ella Inspires Magazine, and more. You can view her complete profile on MuckRacks and explore the section on this website, Why Trust Us?




Amy
Monday 20th of May 2024
Loved your post! A great 10-day itinerary. And your suggestion to "get lost" in Venice is dear to my heart. That's exactly what I do when I'm there for at least one day. The first time I took my kids to Venice they were 9 (twins!), and on our last day there we shut off Google maps and told the the kids to lead the way. My husband and I followed them all over the city and that's how we discovered the beautiful neighborhood of Cannaregio for the first time.
thattexascouple
Tuesday 21st of May 2024
Hi Amy! Thank you so much for reading and for sharing this great story with us! I love it!
Jenn | By Land and Sea
Monday 20th of May 2024
Italy is a country I just can't get enough of! You've featured so many great places and tips here! Makes me want to go back... again and again!
thattexascouple
Monday 20th of May 2024
Thank you so much, Jenn. Italy is an amazing destination, and truly, my favorite place on Earth!
Stephanie
Sunday 19th of May 2024
What great advice on the number of hotels for a 10 day trip!
thattexascouple
Monday 20th of May 2024
Thank you so much, Stephanie!
Susan
Sunday 19th of May 2024
This is such a great itinerary! This is very similar to what I did for my first trip to Italy - my first solo international trip. I'd love to go back now that I'm slightly older and much wiser ;)
thattexascouple
Monday 20th of May 2024
That is so great to hear. We try to incorporate Italy into all of our trips to Europe. LOL!
Liz
Saturday 16th of July 2022
Do you recommend flying in and out of Rome or flying out of Venice at the end of your trip?
thattexascouple
Monday 18th of July 2022
Hi Liz! Personally, I would fly out of whatever city you end in. So, if you are ending in Venice, then I would fly out of Venice for sure.